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Infection, reinfection, and vaccination under suboptimal immune protection: epidemiological perspectives.

Abstract:

The SIR (susceptible-infectious-resistant) and SIS (susceptible-infectious-susceptible) frameworks for infectious disease have been extensively studied and successfully applied. They implicitly assume the upper and lower limits of the range of possibilities for host immune response. However, the majority of infections do not fall into either of these extreme categories. We combine two general avenues that straddle this range: temporary immune protection (immunity wanes over time since infecti...

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Publication status:
Published

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Publisher copy:
10.1016/j.jtbi.2004.02.015

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Journal:
Journal of theoretical biology
Volume:
228
Issue:
4
Pages:
539-549
Publication date:
2004-06-01
DOI:
EISSN:
1095-8541
ISSN:
0022-5193
Source identifiers:
449655
Language:
English
Keywords:
Pubs id:
pubs:449655
UUID:
uuid:b633bce4-353d-4832-87e6-e3d240cf52c4
Local pid:
pubs:449655
Deposit date:
2014-02-26

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