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Thesis

A transcriptomic and electrophysiological characterisation of the rat stellate ganglia in health and disease

Abstract:

Hypertension represents a major health burden in both the developed and developing world. A significant component of hypertension is abnormal activation of the sympathetic nervous system, which is associated with a wide spectrum of serious co-morbidities. However, the molecular mechanisms behind this are poorly understood, as are the biophysical properties underlying heightened cardiac sympathetic activity in the prehypertensive state. This thesis utilised large-scale transcriptomics, comb...

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Division:
MSD
Department:
Doctoral Training Centre - MSD
Oxford college:
Green Templeton College
Role:
Author
ORCID:
0000-0003-2225-4020

Contributors

Role:
Supervisor
Role:
Supervisor
ORCID:
0000-0001-8453-6133
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Programme:
OXION
Grant:
BST0008Z
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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