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Journal article

The role of cytotoxic T-cells in HIV infection.

Abstract:

HIV-specific cytotoxic T lymphocytes (CTL) are believed to play a major role in controlling virus levels through the asymptomatic period of HIV infection. For the rational design of an HIV vaccine, we need to know whether protective immunity can ever develop following HIV exposure in people who remain uninfected. We have detected HIV-specific CTL in 5/6 repeatedly exposed, persistently seronegative female sex-workers in The Gambia. Their CTL, repeatedly detected over two years, recognise epit...

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Publication status:
Published

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Authors


Rowland-Jones, S More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
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Journal:
Developments in biological standardization
Volume:
92
Pages:
209-214
Publication date:
1998
ISSN:
0301-5149
URN:
uuid:b60625cf-e295-448d-946a-d9e02e52694e
Source identifiers:
95282
Local pid:
pubs:95282

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