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Journal article

The role of cytotoxic T-cells in HIV infection.

Abstract:

HIV-specific cytotoxic T lymphocytes (CTL) are believed to play a major role in controlling virus levels through the asymptomatic period of HIV infection. For the rational design of an HIV vaccine, we need to know whether protective immunity can ever develop following HIV exposure in people who remain uninfected. We have detected HIV-specific CTL in 5/6 repeatedly exposed, persistently seronegative female sex-workers in The Gambia. Their CTL, repeatedly detected over two years, recognise epit...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
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Journal:
Developments in biological standardization
Volume:
92
Pages:
209-214
Publication date:
1998-01-01
ISSN:
0301-5149
Source identifiers:
95282
Language:
English
Keywords:
Pubs id:
pubs:95282
UUID:
uuid:b60625cf-e295-448d-946a-d9e02e52694e
Local pid:
pubs:95282
Deposit date:
2012-12-19

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