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Plasma exchange and glucocorticoids in severe anca-associated vasculitis

Abstract:

BACKGROUND More effective and safer treatments are needed for antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis. METHODS We conducted a randomized trial with a 2-by-2 factorial design to evaluate the use of plasma exchange and two regimens of oral glucocorticoids in patients with severe ANCA-associated vasculitis (defined by an estimated glomerular filtration rate of <50 ml per minute per 1.73 m2 of body-surface area or diffuse pulmonary hemorrhage). Patients were randomly ass...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1056/nejmoa1803537

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Role:
Author
ORCID:
0000-0003-3573-9203
Publisher:
Massachusetts Medical Society
Journal:
New England Journal of Medicine More from this journal
Volume:
382
Issue:
7
Pages:
622-631
Publication date:
2020-02-13
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
Language:
English
Keywords:
Pubs id:
1173550
Local pid:
pubs:1173550
Deposit date:
2021-04-26

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