Journal article icon

Journal article

The life, death and regenerative ability of immature and mature rat retinal ganglion cells are influenced by their birthdate.

Abstract:

The extensive period of retinal ganglion cell (RGC) neurogenesis in the rat is associated with a protracted sequence of arrival of their axons into central targets such as the superior colliculus (SC) (Dallimore et al., 2002). Using in utero 5-bromo-2'-deoxyrudine (BrdU) injections to label early (embryonic day (E) 15) or late (E18 or E19) born RGCs, we now show that E15 RGCs with axons that enter the SC prenatally undergo programmed cell death earlier than late-born RGCs whose axons only rea...

Expand abstract

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
Journal:
Experimental neurology
Volume:
225
Issue:
2
Pages:
353-365
Publication date:
2010-10-05
DOI:
EISSN:
1090-2430
ISSN:
0014-4886
URN:
uuid:b596c2bf-880e-40e0-93f9-348b20fea366
Source identifiers:
95268
Local pid:
pubs:95268

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP