Journal article icon

Journal article

The interaction of the molecular chaperone alpha-crystallin with unfolding alpha-lactalbumin: a structural and kinetic spectroscopic study.

Abstract:

The unfolding of the apo and holo forms of bovine alpha-lactalbumin (alpha-LA) upon reduction by dithiothreitol (DTT) in the presence of the small heat-shock protein alpha-crystallin, a molecular chaperone, has been monitored by visible and UV absorption spectroscopy, mass spectrometry and (1)H NMR spectroscopy. From these data, a description and a time-course of the events that result from the unfolding of both forms of the protein, and the state of the protein that interacts with alpha-crys...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Expand authors...
Journal:
Journal of molecular biology
Volume:
318
Issue:
3
Pages:
815-827
Publication date:
2002-05-05
DOI:
EISSN:
1089-8638
ISSN:
0022-2836
URN:
uuid:b53fb0e9-bb90-4a9a-9029-0f612b87274b
Source identifiers:
100594
Local pid:
pubs:100594

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP