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Adverse events associated with unblinded, but not with blinded, statin therapy in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid-Lowering Arm (ASCOT-LLA): a randomised double-blind placebo-controlled trial and its non-randomised non-blind extension phase

Abstract:

BACKGROUND: In blinded randomised controlled trials, statin therapy has been associated with few adverse events (AEs). By contrast, in observational studies, larger increases in many different AEs have been reported than in blinded trials.

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1016/S0140-6736(17)31075-9

Authors


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Servier Research Group More from this funder
Leo Laboratories More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Lancet Journal website
Volume:
389
Issue:
10088
Pages:
2473-2481
Publication date:
2017-05-02
Acceptance date:
2017-02-22
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Pubs id:
pubs:695813
URN:
uri:b53478e9-9cc0-4aca-9461-2794a39b8c3f
UUID:
uuid:b53478e9-9cc0-4aca-9461-2794a39b8c3f
Local pid:
pubs:695813
Language:
English
Keywords:

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