Journal article icon

Journal article

A pooled analysis of 2 placebo-controlled 18-month trials of lamotrigine and lithium maintenance in bipolar I disorder.

Abstract:

BACKGROUND: Two clinical trials, prospectively designed for combined analysis, compared placebo, lithium, and lamotrigine for treatment of bipolar I disorder in recently depressed or manic patients. METHOD: 1315 bipolar I patients (DSM-IV) enrolled in the initial open-label phase, and 638 were stabilized and randomly assigned to 18 months of double-blind monotherapy with lamotrigine (N = 280; 50-400 mg/day fixed dose or 100-400 mg/day flexible dose), lithium (N = 167; serum level of 0.8-1.1 ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.4088/JCP.v65n0321

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Bowden, CL More by this author
Calabrese, JR More by this author
Expand authors...
Journal:
The Journal of clinical psychiatry
Volume:
65
Issue:
3
Pages:
432-441
Publication date:
2004-03-05
DOI:
EISSN:
1555-2101
ISSN:
0160-6689
URN:
uuid:b51ab214-9930-4c81-9232-659fd9657f16
Source identifiers:
97886
Local pid:
pubs:97886

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP