Journal article

How to contain artemisinin- and multidrug-resistant Falciparum malaria

Abstract:: In the Greater Mekong subregion (GMS), artemisinin resistance is increasingly compounded by partner drug resistance, causing high failure rates of artemisinin combination therapies in some areas. For its containment, an accelerated elimination strategy will be needed. This includes high-quality implementation of conventional malaria control measures: early case management with quality artemisinin combination therapies (avoiding artesunate monotherapies) and single gametocytocidal low dose of primaquine, vector control and surveillance. Village health workers (VHWs) play a key role in the provision of community-based services which have to reach even the most remote populations. Additional, more aggressive, approaches will be important to accelerate malaria elimination, which could include mass drug administrations, potentially in combination with ivermectin and vaccination, mass screening and treatment with novel diagnostics, reactive case detection, and other measures.

Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Dondorp, A., Smithuis, F., Woodrow, C., & von Seidlein, L. (2017). How to contain artemisinin- and multidrug-resistant Falciparum malaria. Trends in Parasitology, 33(5), 353–363.

MLA Style

Dondorp, A., et al. “How to Contain Artemisinin- and Multidrug-Resistant Falciparum Malaria.” Trends in Parasitology, vol. 33, no. 5, Cell Press, 2017, pp. 353–63.

Chicago Style

Dondorp, A, F Smithuis, C Woodrow, and L von Seidlein. 2017. “How to Contain Artemisinin- and Multidrug-Resistant Falciparum Malaria.” Trends in Parasitology 33 (5): 353–63.
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Files:: Dondorp-et-al-2017-Trends-in-Parasitology.pdf

(Preview, Version of record, pdf, 1.9MB, Terms of use)

Publisher copy:: 10.1016/j.pt.2017.01.004

Authors

+ Dondorp, A More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Tropical Medicine
Role:: Author

+ Smithuis, F More by this author

Institution:: University of Oxford
Oxford college:: Nuffield College
Role:: Author

+ Woodrow, C More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Tropical Medicine
Role:: Author

+ von Seidlein, L More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Tropical Medicine
Role:: Author

Publisher:: Cell Press
Journal:: Trends in Parasitology More from this journal
Volume:: 33
Issue:: 5
Pages:: 353-363
Publication date:: 2017-02-07
DOI:: 10.1016/j.pt.2017.01.004
EISSN:: 1471-5007
ISSN:: 1471-4922

Language:: English
Pubs id:: pubs:679917
UUID:: uuid:b4cdd020-3b0d-4b89-8dcd-a7a78483d230
Local pid:: pubs:679917
Source identifiers:: 679917
Deposit date:: 2017-03-08

Terms of use

Copyright holder:: Dondorp et al
Copyright date:: 2017
Notes:: © 2017 The Authors. Published by Elsevier Ltd. This is an open access article under the CC-BY license (http://creativecommons.org/licenses/by/4.0/).

Licence:: CC Attribution (CC BY)

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