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Prognostic significance of reduced red blood cell deformability in severe falciparum malaria.

Abstract:

Severe falciparum malaria is associated with microvascular obstruction resulting from sequestration of erythrocytes containing mature stages of the parasite. Since reduced red blood cell deformability (RBC-D) can contribute to impaired microcirculatory flow, RBC-D was measured in 23 patients with severe falciparum malaria (seven of whom subsequently died), 30 patients with uncomplicated malaria, and 17 healthy controls. The RBC-D, measured by ektacytometry, was significantly reduced in severe...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Hardeman, MR More by this author
Chotivanich, KT More by this author
Silamut, K More by this author
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Journal:
The American journal of tropical medicine and hygiene
Volume:
57
Issue:
5
Pages:
507-511
Publication date:
1997-11-05
EISSN:
1476-1645
ISSN:
0002-9637
URN:
uuid:b478838a-ced7-4953-b63e-6669b59d3184
Source identifiers:
36123
Local pid:
pubs:36123

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