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Journal article

Genetic associations with white matter hyperintensities confer risk of lacunar stroke

Abstract:

Background and Purpose— White matter hyperintensities (WMH) are increased in patients with lacunar stroke. Whether this is because of shared pathogenesis remains unknown. Using genetic data, we evaluated whether WMH-associated genetic susceptibility factors confer risk of lacunar stroke, and therefore whether they share pathogenesis.

Methods— We used a genetic risk score approach to test whether single nucleotide polymorphisms associated with WMH in community populati...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Version of record

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Publisher copy:
10.1161/STROKEAHA.115.011625

Authors


Traylor, M More by this author
Rutten-Jacobs, LC More by this author
Holliday, EG More by this author
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Publisher:
American Heart Association Publisher's website
Journal:
Stroke Journal website
Volume:
47
Issue:
5
Pages:
1174-1179
Publication date:
2016-04-12
Acceptance date:
2016-03-09
DOI:
EISSN:
1524-4628
ISSN:
0039-2499
Pubs id:
pubs:616777
URN:
uri:b45ac896-0578-4eab-ad42-429536eced81
UUID:
uuid:b45ac896-0578-4eab-ad42-429536eced81
Local pid:
pubs:616777

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