Journal article
In vivo MRI characterization of progressive cardiac dysfunction in the mdx mouse model of muscular dystrophy.
- Abstract:
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AIMS: The mdx mouse has proven to be useful in understanding the cardiomyopathy that frequently occurs in muscular dystrophy patients. Here we employed a comprehensive array of clinically relevant in vivo MRI techniques to identify early markers of cardiac dysfunction and follow disease progression in the hearts of mdx mice. METHODS AND RESULTS: Serial measurements of cardiac morphology and function were made in the same group of mdx mice and controls (housed in a non-SPF facility) using MRI ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 1.5MB, Terms of use)
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- Publisher copy:
- 10.1371/journal.pone.0028569
Authors
Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PloS one More from this journal
- Volume:
- 7
- Issue:
- 1
- Article number:
- e28569
- Publication date:
- 2012-01-01
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
Item Description
- Language:
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English
- Keywords:
- UUID:
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uuid:b42b62ff-8a41-468c-8f80-80930e80ba4b
- Local pid:
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pubs:237346
- Source identifiers:
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237346
- Deposit date:
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2012-12-19
Terms of use
- Copyright holder:
- Stuckey et al
- Copyright date:
- 2012
- Notes:
- Copyright 2012 Stuckey et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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