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Oxygenase catalyzed 5-methylcytosine hydroxylation.

Abstract:
Recent reports identify the oxygenase catalyzed production of 5-hydroxymethylcytosine as a modification to mammalian DNA (Kriaucionis and Heintz, 2009; Tahiliani et al., 2009). This discovery has potential far-reaching implications for epigenetic regulation and will stimulate efforts to identify new nucleic acid modifications.
Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Journal:
Chemistry and biology
Volume:
16
Issue:
6
Pages:
580-583
Publication date:
2009-06-05
DOI:
EISSN:
1879-1301
ISSN:
1074-5521
URN:
uuid:b3b349cc-1173-4d34-8ebe-5f5cbd8625ac
Source identifiers:
34771
Local pid:
pubs:34771

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