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Clinical impact and reliability of pleural fluid mesothelin in undiagnosed pleural effusions.

Abstract:

RATIONALE: Serum mesothelin is a new biomarker for the diagnosis of mesothelioma. Patients with mesothelioma commonly present with pleural effusions. To define the clinical utility of mesothelin quantification in pleural fluid, we assessed its additional value over pleural fluid cytology and its short-term reproducibility and reliability after pleural inflammatory processes, including pleurodesis. OBJECTIVES: To assess the diagnostic role of pleural fluid mesothelin and the effect of common c...

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Publication status:
Published

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Publisher copy:
10.1164/rccm.200811-1729oc

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
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Journal:
American journal of respiratory and critical care medicine
Volume:
180
Issue:
5
Pages:
437-444
Publication date:
2009-09-05
DOI:
EISSN:
1535-4970
ISSN:
1073-449X
URN:
uuid:b3a91c0b-805e-4494-b33a-56ab0d92be59
Source identifiers:
20432
Local pid:
pubs:20432

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