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The where and when of T cell regulation in transplantation

Abstract:

Multiple cell types contribute to the peripheral regulation of T cell alloresponses in haematopoieitc cell transplantation (HCT) and solid organ transplantation (SOT). Of these, regulatory T cells (Tregs) are the principal players and have shown the greatest success in the therapeutic control of detrimental immune responses. Investigations into the induction, location, and mechanism of suppression utilised by Tregs to control alloreactive responses are ongoing. The activation and homing chara...

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Publisher copy:
10.1016/j.it.2012.11.003

Authors


Journal:
Trends in Immunology
Volume:
34
Issue:
3
Pages:
107-113
Publication date:
2013-03-05
DOI:
EISSN:
1471-4981
ISSN:
1471-4906
URN:
uuid:b36d28c4-3ea8-4019-8ae0-017f7c3630dd
Source identifiers:
395290
Local pid:
pubs:395290

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