Journal article
Modelling the cascade of biomarker changes in <i>GRN</i>-related frontotemporal dementia
- Abstract:
- Degeneration of axons and language deficits are indicated to be the earliest biomarkers in FTD-GRN, with bvFTD being more heterogeneous in disease progression than nfvPPA. Our data-driven model could help identify presymptomatic GRN mutation carriers at risk of conversion to the clinical stage.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 1.5MB, Terms of use)
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- Publisher copy:
- 10.1136/jnnp-2020-323541
Authors
+ Nederlandse Organisatie voor Wetenschappelijk Onderzoek
More from this funder
- Funder identifier:
- 10.13039/501100003246
- Grant:
- 016-130-677
+ Alzheimer Nederland
More from this funder
- Funder identifier:
- 10.13039/501100010969
- Grant:
- WE.09-2014-4
+ Horizon 2020 Framework Programme
More from this funder
- Funder identifier:
- 10.13039/100010661
- Grant:
- 666992
- Publisher:
- BMJ Publishing Group
- Journal:
- Journal of Neurology, Neurosurgery and Psychiatry More from this journal
- Volume:
- 92
- Issue:
- 5
- Pages:
- 494-501
- Publication date:
- 2021-01-15
- DOI:
- EISSN:
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1468-330X
- ISSN:
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0022-3050
- Language:
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English
- Keywords:
- Pubs id:
-
1256437
- Local pid:
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pubs:1256437
- Source identifiers:
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W3120209873
- Deposit date:
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2026-04-24
- ARK identifier:
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Terms of use
- Copyright date:
- 2021
- Licence:
- CC Attribution (CC BY)
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