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Evaluating the links between schizophrenia and sleep and circadian rhythm disruption.

Abstract:

Sleep and circadian rhythm disruption (SCRD) and schizophrenia are often co-morbid. Here, we propose that the co-morbidity of these disorders stems from the involvement of common brain mechanisms. We summarise recent clinical evidence that supports this hypothesis, including the observation that the treatment of SCRD leads to improvements in both the sleep quality and psychiatric symptoms of schizophrenia patients. Moreover, many SCRD-associated pathologies, such as impaired cognitive perform...

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Publication status:
Published

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Publisher copy:
10.1007/s00702-012-0817-8

Authors


Pritchett, D More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Oliver, PL More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
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Journal:
Journal of neural transmission (Vienna, Austria : 1996)
Volume:
119
Issue:
10
Pages:
1061-1075
Publication date:
2012-10-05
DOI:
EISSN:
1435-1463
ISSN:
0300-9564
URN:
uuid:b2de9515-17e6-4f64-a452-fcaf28e3a6df
Source identifiers:
328991
Local pid:
pubs:328991

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