Journal article
Homochiral carbon branched piperidines from carbon branched sugar lactones: 4-C-methyl-deoxyfuconojirimycin (DFJ) and its enantiomer - removal of glycosidase inhibition
- Abstract:
- The value of readily available 2-C-methyl aldonic acids in short syntheses of carbon branched piperidines containing quaternary centers is demonstrated. The effect of the introduction of a 4-C-methyl group into piperidine imino sugar inhibitors of l-fucosidases and d-galactosidases is reported. © 2007 Elsevier Ltd. All rights reserved.
- Publication status:
- Published
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Authors
- Journal:
- TETRAHEDRON-ASYMMETRY More from this journal
- Volume:
- 18
- Issue:
- 4
- Pages:
- 500-512
- Publication date:
- 2007-03-12
- DOI:
- EISSN:
-
1362-511X
- ISSN:
-
0957-4166
- Language:
-
English
- Pubs id:
-
pubs:40327
- UUID:
-
uuid:b2cae2ab-0735-4d03-8aff-411d561bc401
- Local pid:
-
pubs:40327
- Source identifiers:
-
40327
- Deposit date:
-
2012-12-19
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- Copyright date:
- 2007
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