Journal article icon

Journal article

Homochiral carbon branched piperidines from carbon branched sugar lactones: 4-C-methyl-deoxyfuconojirimycin (DFJ) and its enantiomer - removal of glycosidase inhibition

Abstract:
The value of readily available 2-C-methyl aldonic acids in short syntheses of carbon branched piperidines containing quaternary centers is demonstrated. The effect of the introduction of a 4-C-methyl group into piperidine imino sugar inhibitors of l-fucosidases and d-galactosidases is reported. © 2007 Elsevier Ltd. All rights reserved.
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1016/j.tetasy.2007.02.001

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
TETRAHEDRON-ASYMMETRY More from this journal
Volume:
18
Issue:
4
Pages:
500-512
Publication date:
2007-03-12
DOI:
EISSN:
1362-511X
ISSN:
0957-4166


Language:
English
Pubs id:
pubs:40327
UUID:
uuid:b2cae2ab-0735-4d03-8aff-411d561bc401
Local pid:
pubs:40327
Source identifiers:
40327
Deposit date:
2012-12-19

Terms of use



Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP