Journal article icon

Journal article

Whole-exome sequencing of 228 patients with sporadic Parkinson's disease.

Abstract:

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder, affecting 1% of the population over 65 years characterized clinically by both motor and non-motor symptoms accompanied by the preferential loss of dopamine neurons in the substantia nigra pars compacta. Here, we sequenced the exomes of 244 Parkinson’s patients selected from the Oxford Parkinson’s Disease Centre Discovery Cohort and, after quality control, 228 exomes were available for analyses. The PD patient exo...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1038/srep41188

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Expand authors...
Dementias and Neurodegenerative Diseases Research Network More from this funder
National Institute for Health Research More from this funder
More from this funder
Grant:
Monument Trust Discovery Award
Publisher:
Nature Publishing Group Publisher's website
Journal:
Scientific Reports Journal website
Volume:
7
Pages:
41188
Publication date:
2017-01-01
Acceptance date:
2016-12-16
DOI:
ISSN:
2045-2322
Language:
English
Keywords:
Pubs id:
pubs:673199
UUID:
uuid:b2a5a2d5-ef02-4b2f-8d38-1d3106987e61
Local pid:
pubs:673199
Deposit date:
2017-02-14

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP