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Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.

Abstract:

To identify genetic loci influencing central obesity and fat distribution, we performed a meta-analysis of 16 genome-wide association studies (GWAS, N = 38,580) informative for adult waist circumference (WC) and waist-hip ratio (WHR). We selected 26 SNPs for follow-up, for which the evidence of association with measures of central adiposity (WC and/or WHR) was strong and disproportionate to that for overall adiposity or height. Follow-up studies in a maximum of 70,689 individuals identified t...

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Publication status:
Published

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Journal:
PLoS genetics
Volume:
5
Issue:
6
Pages:
e1000508
Publication date:
2009-06-05
DOI:
EISSN:
1553-7404
ISSN:
1553-7390
URN:
uuid:b2a534ff-9fd8-44e3-a56f-8bcb3360be59
Source identifiers:
11592
Local pid:
pubs:11592

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