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Journal article

Artificial intelligence in inflammatory bowel disease endoscopy: implications for clinical trials

Abstract:
Artificial intelligence shows promise for clinical research in inflammatory bowel disease endoscopy. Accurate assessment of endoscopic activity is important in clinical practice and inflammatory bowel disease clinical trials. Emerging artificial intelligence technologies can increase efficiency and accuracy of assessing the baseline endoscopic appearance in patients with inflammatory bowel disease and the impact that therapeutic interventions may have on mucosal healing in both of these contexts. In this review, state-of-the-art endoscopic assessment of mucosal disease activity in inflammatory bowel disease clinical trials is described, covering the potential for artificial intelligence to transform the current paradigm, its limitations, and suggested next steps. Site-based artificial intelligence quality evaluation and inclusion of patients in clinical trials without the need for a central reader is proposed; for following patient progress, a second reading using AI alongside a central reader with expedited reading is proposed. Artificial intelligence will support precision endoscopy in inflammatory bowel disease and is on the threshold of advancing inflammatory bowel disease clinical trial recruitment.
Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1093/ecco-jcc/jjad029

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
ORCID:
0000-0001-8035-3700
More by this author
Role:
Author
ORCID:
0000-0002-5247-940X
More by this author
Role:
Author
ORCID:
0000-0002-2690-4361


Publisher:
Oxford University Press
Journal:
Journal of Crohn's and Colitis More from this journal
Volume:
17
Issue:
8
Pages:
1342–1353
Place of publication:
England
Publication date:
2023-02-22
Acceptance date:
2023-02-22
DOI:
EISSN:
1876-4479
ISSN:
1873-9946
Pmid:
36812142


Language:
English
Keywords:
Pubs id:
1331464
Local pid:
pubs:1331464
Deposit date:
2023-03-23

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