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Synthesis of metallo-beta-lactamase inhibitors

Abstract:
α-Amido trifluoromethyl alcohols and ketones were synthesised via two independent routes using the Ruppert Reagent (TMS-CF3) and shown to be inhibitors of metallo-β-lactamases.
Publication status:
Published

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Publisher copy:
10.1016/S0040-4020(97)00404-3

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
TETRAHEDRON More from this journal
Volume:
53
Issue:
21
Pages:
7275-7290
Publication date:
1997-05-26
DOI:
ISSN:
0040-4020


Language:
English
Pubs id:
pubs:45496
UUID:
uuid:b20952f2-511c-4030-b416-f10fe2ef6d8a
Local pid:
pubs:45496
Source identifiers:
45496
Deposit date:
2012-12-19

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