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Metabolic profiling in Maturity-onset diabetes of the young (MODY) and young onset type 2 diabetes fails to detect robust urinary biomarkers.

Abstract:

It is important to identify patients with Maturity-onset diabetes of the young (MODY) as a molecular diagnosis determines both treatment and prognosis. Genetic testing is currently expensive and many patients are therefore not assessed and are misclassified as having either type 1 or type 2 diabetes. Biomarkers could facilitate the prioritisation of patients for genetic testing. We hypothesised that patients with different underlying genetic aetiologies for their diabetes could have distinct ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0040962

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
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Institution:
University of Oxford
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Institution:
University of Oxford
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Institution:
University of Oxford
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Institution:
University of Oxford
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Funding agency for:
Gloyn, AL
European Union More from this funder
National Institute for Health Research (NIHR) Oxford Biomedical Research Centre More from this funder
European Community More from this funder
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Publisher:
Public Library of Science Publisher's website
Journal:
PloS One Journal website
Volume:
7
Issue:
7
Pages:
Article: e40962
Publication date:
2012
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
URN:
uuid:b1fe9f09-3ca2-4e1b-89ea-df7a635d36e2
Source identifiers:
344353
Local pid:
pubs:344353

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