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Brain structural and functional connectivity and the progression of neuropathology in Alzheimer's disease

Abstract:

In our contribution to this special issue focusing on advances in Alzheimer's disease (AD) research since the centennial, we will briefly review some of our own studies applying magnetic resonance imaging (MRI) measures of function and connectivity for characterization of genetic contributions to the neuropathology of AD and as candidate biomarkers. We review how functional MRI during both memory encoding and at rest is able to define APOE4 genotype-dependent physiological changes decades bef...

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
Volume:
3
Pages:
163-172
Publication date:
2012-01-01
DOI:
EISSN:
2210-5735
ISSN:
2210-5727
URN:
uuid:b1d37d89-a7ca-45bb-b705-861dba67fb02
Source identifiers:
403724
Local pid:
pubs:403724
ISBN:
9781614991533

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