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Dopamine-dependent architecture of cortico-subcortical network connectivity.

Abstract:

Maladaptive dopaminergic mediation of reward processing in humans is thought to underlie multiple neuropsychiatric disorders, including addiction, Parkinson's disease, and schizophrenia. Mechanisms responsible for the development of such disorders may depend on individual differences in neural signaling within large-scale cortico-subcortical circuitry. Using a combination of functional neuroimaging and pharmacological challenges in healthy volunteers, we identified opposing dopamine agonistic...

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Publication status:
Published

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Publisher copy:
10.1093/cercor/bhs136

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Soeter, RP More by this author
van Gerven, JM More by this author
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Journal:
Cerebral cortex (New York, N.Y. : 1991)
Volume:
23
Issue:
7
Pages:
1509-1516
Publication date:
2013-07-05
DOI:
EISSN:
1460-2199
ISSN:
1047-3211
URN:
uuid:b1bca391-778d-40c0-9ee8-ad79ace4723e
Source identifiers:
386548
Local pid:
pubs:386548

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