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Journal article

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium.

Abstract:

Quantitative ultrasound of the heel captures heel bone properties that independently predict fracture risk and, with bone mineral density (BMD) assessed by X-ray (DXA), may be convenient alternatives for evaluating osteoporosis and fracture risk. We performed a meta-analysis of genome-wide association (GWA) studies to assess the genetic determinants of heel broadband ultrasound attenuation (BUA; n = 14 260), velocity of sound (VOS; n = 15 514) and BMD (n = 4566) in 13 discovery cohorts. Indep...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/ddt675

Authors


Moayyeri, A More by this author
Karasik, D More by this author
Estrada, K More by this author
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Journal:
Human molecular genetics
Volume:
23
Issue:
11
Pages:
3054-3068
Publication date:
2014-06-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:b1b5a3e1-41e3-4cb7-b72a-98fbe57aa504
Source identifiers:
465815
Local pid:
pubs:465815

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