- Abstract:
-
We demonstrate far-field optical imaging at the nanoscale with unlabeled samples. Subdiffraction resolution images of autofluorescent samples are obtained by depleting the ground state of natural fluorophores by transferring them to a metastable dark state and simultaneously localizing those fluorophores that are transiently returning. Our approach is based on the insight that nanoscopy methods relying on stochastic single-molecule switching require only a single fluorescence on-off cycle to ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1021/nl1027638
-
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- Journal:
- Nano letters
- Volume:
- 10
- Issue:
- 10
- Pages:
- 4249-4252
- Publication date:
- 2010-10-05
- DOI:
- EISSN:
-
1530-6992
- ISSN:
-
1530-6984
- URN:
-
uuid:b10fee5f-5d6c-4baa-b0e0-0425638180e1
- Source identifiers:
-
222199
- Local pid:
- pubs:222199
- Language:
- English
- Keywords:
- Copyright date:
- 2010
Journal article
Far-field autofluorescence nanoscopy.
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