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State of the art of diagnosis of rickettsial diseases: the use of blood specimens for diagnosis of scrub typhus, spotted fever group rickettsiosis, and murine typhus

Abstract:

With improved malaria control, acute undifferentiated febrile illness studies in tropical regions reveal a startling proportion of rickettsial illnesses, especially scrub typhus, murine typhus, and spotted fever group rickettsioses. Laboratory diagnosis of these infections evolved little over the past 40 years, but combinations of technologies like PCR and loop-mediated isothermal amplification, with refined rapid diagnostic tests and/or ELISA, are promising for guidance for early antirickett...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1097/QCO.0000000000000298

Authors


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Department:
Oxford, MSD, NDM, Tropical Medicine
Dumler, JS More by this author
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Funding agency for:
Paris, D
Publisher:
Lippincott, Williams & Wilkins Publisher's website
Journal:
Current Opinion in Infectious Diseases Journal website
Volume:
29
Issue:
5
Pages:
433–439
Publication date:
2016-07-13
Acceptance date:
2016-06-24
DOI:
EISSN:
1473-6527
ISSN:
0951-7375
Pubs id:
pubs:636382
URN:
uri:b10d06ab-554d-492a-81c7-a69fa015cb6d
UUID:
uuid:b10d06ab-554d-492a-81c7-a69fa015cb6d
Local pid:
pubs:636382

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