Clopidogrel-associated acute migratory arthritis following kidney-pancreas transplantation.

Journal article

Clopidogrel is a potent inhibitor of platelet aggregation and has been used as an alternative, or as an adjunct to aspirin in reducing the risk of thrombosis. A 34-year-old uremic type 1 male diabetic patient who underwent simultaneous kidney-pancreas transplantation was given clopidogrel as he was allergic to aspirin. He developed polyarthralgia one week later, followed in a few days by symmetrical migratory polyarthritis, which resolved completely on withdrawing the drug. The implications to clinical management in a transplant setting are discussed.

Authors: Muthusamy, A; Vaidya, A; Friend, P

• Publication status: Published
• Journal: International journal of immunopathology and pharmacology
• Volume: 19
• Issue: 2
• Pages: 443-444
• Publication date: 2006-01-01
• ISSN: 0394-6320
• Language: English
• Keywords: Diabetes Mellitus, Type 1; Ticlopidine; Platelet Aggregation Inhibitors; Postoperative Complications; Pancreas Transplantation; Arthritis; Humans; Kidney Transplantation; Adult; Male; Kidney Function Tests; Uremia