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Journal article

Excessive endometrial PlGF- Rac1 signalling underlies endometrial cell stiffness linked to pre-eclampsia

Abstract:

The decidual transformation during the menstrual cycle is pivotal in preparing the endometrium to support a healthy pregnancy1,2. This physiological adaptation of the endometrium involves changes in cell proliferation, morphology, mechanotransduction responses, immune cell modulation, and vascular remodelling3,4. Disruptions in these processes can result in pregnancy complications such as implantation failure, recurrent miscarriage, or preeclampsia, as well as contribute to cancer progression...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors

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Role:
Author
ORCID:
0000-0002-2597-6910
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Institution:
University of Oxford
Role:
Author


Publisher:
Nature Research
Journal:
Communications Biology More from this journal
Volume:
7
Issue:
1
Pages:
530-530
Publication date:
2024-05-04
DOI:
EISSN:
2399-3642
ISSN:
2399-3642


Language:
English
Keywords:
Pubs id:
1994746
Local pid:
pubs:1994746
Source identifiers:
W4396637040
Deposit date:
2026-03-31
ARK identifier:
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