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Diagnosis of periprosthetic joint infection: The promise of next generation sequencing

Abstract:

Background

Next-generation sequencing (NGS) is a well-established technique for sequencing of DNA and has recently gained attention in many fields of medicine. Our aim was to evaluate the NGS’ accuracy in identifying the causative organism(s) in patients with periprosthetic joint infection (PJI).

Methods

In this prospective study samples were collected from 65 revision arthroplasties (39 knees, 26 hips) and 17 primary arthroplasties (9 hips, 8 knees). Synovial flu...

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Publication status:
In press
Peer review status:
Peer reviewed

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Authors


Tarabichi, M More by this author
Goswami, K More by this author
Silibovsky, R More by this author
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Publisher:
Lippincott, Williams & Wilkins Publisher's website
Journal:
Journal of Bone and Joint Surgery: American Volume Journal website
Publication date:
2017-08-05
Acceptance date:
2017-08-15
ISSN:
1535-1386 and 0021-9355
Pubs id:
pubs:720369
URN:
uri:b0a970b1-8cfc-4882-be99-0b2a4bc0beca
UUID:
uuid:b0a970b1-8cfc-4882-be99-0b2a4bc0beca
Local pid:
pubs:720369

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