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The Cell Physiology of Biphasic Insulin Secretion.

Abstract:
Glucose-stimulated insulin secretion consists of a transient first phase followed by a sustained second phase. Diabetes (type II) is associated with abnormalities in this release pattern. Here we review the evidence that biphasic insulin secretion reflects exocytosis of two functional subsets of secretory granules and the implications for diabetes.
Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author


Journal:
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society More from this journal
Volume:
15
Issue:
2
Pages:
72-77
Publication date:
2000-04-01
EISSN:
1522-161X
ISSN:
0886-1714


Language:
English
Pubs id:
pubs:26184
UUID:
uuid:b0a4f53f-4ee6-4f70-ac95-2e1a8ec03d6d
Local pid:
pubs:26184
Source identifiers:
26184
Deposit date:
2012-12-19
ARK identifier:

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