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Mechanism of auxin perception by the TIR1 ubiquitin ligase.

Abstract:

Auxin is a pivotal plant hormone that controls many aspects of plant growth and development. Perceived by a small family of F-box proteins including transport inhibitor response 1 (TIR1), auxin regulates gene expression by promoting SCF ubiquitin-ligase-catalysed degradation of the Aux/IAA transcription repressors, but how the TIR1 F-box protein senses and becomes activated by auxin remains unclear. Here we present the crystal structures of the Arabidopsis TIR1-ASK1 complex, free and in compl...

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Publication status:
Published

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Publisher copy:
10.1038/nature05731

Authors


Calderon-Villalobos, LI More by this author
Robinson, CV More by this author
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Journal:
Nature
Volume:
446
Issue:
7136
Pages:
640-645
Publication date:
2007-04-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:b05a8e5e-aad4-4f57-b187-7d5648787139
Source identifiers:
59416
Local pid:
pubs:59416

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