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Journal article

Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!).

Abstract:

rVSV-ZEBOV is a recombinant, replication competent vesicular stomatitis virus-based candidate vaccine expressing a surface glycoprotein of Zaire Ebolavirus. We tested the effect of rVSV-ZEBOV in preventing Ebola virus disease in contacts and contacts of contacts of recently confirmed cases in Guinea, west Africa.We did an open-label, cluster-randomised ring vaccination trial (Ebola ça Suffit!) in the communities of Conakry and eight surrounding prefectures in the Basse-Guinée region of Guinea...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S0140-6736(16)32621-6

Authors


More by this author
Institution:
University of Oxford
Department:
NDM
Sub department:
Tropical Medicine
Department:
Unknown
Role:
Author
ORCID:
0000-0002-2469-791X


Publisher:
Elsevier
Journal:
Lancet More from this journal
Volume:
389
Issue:
10068
Pages:
505-518
Publication date:
2016-12-23
Acceptance date:
2016-12-06
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Pmid:
28017403


Language:
English
Keywords:
Pubs id:
pubs:997738
UUID:
uuid:b00c99f2-40b3-4341-8232-dca3238c05ce
Local pid:
pubs:997738
Source identifiers:
997738
Deposit date:
2019-05-29

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