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Journal article

Effects of adjuvant tamoxifen and of cytotoxic therapy on mortality in early breast cancer

Abstract:

We sought information worldwide on mortality according to assigned treatment in all randomized trials that began before 1985 of adjuvant tamoxifen or cytotoxic therapy for early breast cancer (with or without regional lymph-node involvement). Coverage was reasonably complete for most countries. In 28 trials of tamoxifen nearly 4000 of 16,513 women had died, and in 40 chemotherapy trials slightly more than 4000 of 13,442 women had died. The 8106 deaths were approximately evenly distributed ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1056/NEJM198812293192601

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Publisher:
Massachusetts Medical Society
Journal:
New England Journal of Medicine More from this journal
Volume:
319
Issue:
26
Pages:
1681-1692
Publication date:
1988-12-29
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
Language:
English
Pubs id:
pubs:92445
UUID:
uuid:b006d3f5-86f3-4aeb-84db-7eb9a977dc19
Local pid:
pubs:92445
Source identifiers:
92445
Deposit date:
2012-12-19

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