It feels real: physiological responses to a stressful virtual reality environment and its impact on working memory

Journal article

Background Virtual reality (VR) is increasingly used to study and treat psychiatric disorders. Its fidelity depends in part on the extent to which the VR environment provides a convincing simulation, for example whether a putatively stressful VR situation actually produces a stress response.

Methods We studied the stress response in 28 healthy men exposed either to a stressor VR elevator (which simulated travelling up the outside of a tall building and culminated in the participant being asked to step off the elevator platform), or to a control elevator. We measured psychological and physiological (salivary cortisol and alpha-amylase, blood pressure, pulse, skin conductance) stress indices. We also measured subsequent performance on the N-back task because acute stress has been reported to impact on working memory.

Results Compared to participants in the control elevator, those in the external elevator had increases in skin conductance, pulse and subjective stress and anxiety ratings, altered heart rate variability, and a delayed rise in cortisol. N-back performance was unaffected.

Conclusions A putatively stressful VR elevator produces a physiological as well as a psychological stress response, supporting its use in the investigation and treatment of stress-related disorders, and its potential value as an experimental laboratory stressor.

Authors: Martens, M; Antley, A; Freeman, D; Slater, M; Harrison, PJ

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: SAGE Publications
• Journal: Journal of Psychopharmacology
• Volume: 33
• Issue: 10
• Pages: 1264-1273
• Publication date: 2019-07-11
• Acceptance date: 2019-06-07
• DOI: 10.1177/0269881119860156
• EISSN: 1461-7285
• ISSN: 0269-8811
• Keywords: virtual reality; stress; cortisol