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Development and validation of a point-of-care breath test for octane detection

Abstract:

Background: There is a demand for a non-invasive bedside method to diagnose Acute Respiratory Distress Syndrome (ARDS). Octane was discovered and validated as the most important breath biomarker for diagnosis of ARDS using gas-chromatography and mass-spectrometry (GC-MS). However, GC-MS is unsuitable as a point-of-care (POC) test in the intensive care unit (ICU). Therefore, we determined if a newly developed POC breath test can reliably detect octane in exhaled breath...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1039/d1an00378j

Authors


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Role:
Author
ORCID:
0000-0003-4629-4465
More by this author
Role:
Author
ORCID:
0000-0001-7843-3568
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Role:
Author
ORCID:
0000-0001-9938-6035
Publisher:
Royal Society of Chemistry
Journal:
Analyst More from this journal
Volume:
146
Issue:
14
Pages:
4605-4614
Publication date:
2021-06-16
Acceptance date:
2021-06-10
DOI:
EISSN:
1364-5528
ISSN:
0003-2654
Pmid:
34160491
Language:
English
Keywords:
Pubs id:
1185413
Local pid:
pubs:1185413
Deposit date:
2022-01-11

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