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Journal article : Review

Single or combined immune checkpoint inhibitors compared to first‐line platinum‐based chemotherapy with or without bevacizumab for people with advanced non‐small cell lung cancer

Abstract:

Background

Immune checkpoint inhibitors (ICIs) targeting the PD‐1/PD‐L1 axis have changed the first‐line treatment of people with advanced non‐small cell lung cancer (NSCLC). Single‐agent pembrolizumab (a PD‐1 inhibitor) is currently the standard of care as monotherapy in patients with PD‐L1 expression ≥ 50%, either alone or in combination with chemotherapy when PD‐L1 expression is less than 50%. Atezolizumab (PD‐L1 inhibitor) has also been approved in combination ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/14651858.cd013257.pub3

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
NPEU
Role:
Author


Publisher:
Cochrane Collaboration
Journal:
Cochrane Database of Systematic Reviews More from this journal
Volume:
2021
Issue:
4
Article number:
CD013257
Publication date:
2021-04-30
DOI:
EISSN:
1469-493X
Pmid:
33930176


Language:
English
Keywords:
Subtype:
Review
Pubs id:
1175092
Local pid:
pubs:1175092
Deposit date:
2021-06-01
ARK identifier:

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