- Abstract:
-
A mathematical model is proposed to explain the observed internalization of microspheres and 3H-thymidine labelled cells in steady-state multicellular spheroids. The model uses the conventional ideas of nutrient diffusion and consumption by the cells. In addition, a very simple model of the progress of the cells through the cell cycle is considered. Cells are divided into two classes, those proliferating (being in G1, S, G2 or M phases) and those that are quiescent (being in G0). Furthermore,...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1006/bulm.2000.0217
-
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- Journal:
- Bulletin of mathematical biology
- Volume:
- 63
- Issue:
- 2
- Pages:
- 231-257
- Publication date:
- 2001-03-05
- DOI:
- EISSN:
-
1522-9602
- ISSN:
-
0092-8240
- URN:
-
uuid:af42e856-6c35-4ad0-b366-e88d13c1dca2
- Source identifiers:
-
357624
- Local pid:
- pubs:357624
- Copyright date:
- 2001
Journal article
The migration of cells in multicell tumor spheroids.
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