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CNVs into the wild: screening the genomes of conifer trees (Picea spp.) reveals fewer gene copy number variations in hybrids and links to adaptation

Abstract:

Copy number variations (CNVs) have been linked to different phenotypes in human, including many diseases. A genome-scale understanding of CNVs is available in a few plants but none are wild species, leaving a knowledge gap regarding their genome biology and evolutionary role. We developed a reliable CNV detection method for species lacking contiguous reference genome. We selected multiple probes within 14,078 gene sequences and developed comparative genome hybridization on arrays. Gene CNVs w...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s12864-016-3458-8

Authors


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Role:
Author
ORCID:
0000-0002-4839-3857
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Institution:
University of Oxford
Division:
MPLS
Department:
Plant Sciences
Oxford college:
Linacre College
Role:
Author
ORCID:
0000-0002-4883-195X
Publisher:
BioMed Central
Journal:
BMC Genomics More from this journal
Volume:
18
Issue:
1
Article number:
97
Publication date:
2017-01-18
Acceptance date:
2016-12-22
DOI:
EISSN:
1471-2164
Pmid:
28100184
Language:
English
Keywords:
Pubs id:
pubs:675614
UUID:
uuid:aecb93af-ca8f-4344-9e9a-792f030e2bce
Local pid:
pubs:675614
Source identifiers:
675614
Deposit date:
2019-06-27

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