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Variability in cardiac electrophysiology: Using experimentally-calibrated populations of models to move beyond the single virtual physiological human paradigm.

Abstract:

Physiological variability manifests itself via differences in physiological function between individuals of the same species, and has crucial implications in disease progression and treatment. Despite its importance, physiological variability has traditionally been ignored in experimental and computational investigations due to averaging over samples from multiple individuals. Recently, modelling frameworks have been devised for studying mechanisms underlying physiological variability in card...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.pbiomolbio.2015.12.002

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Role:
Author
Publisher:
Elsevier
Journal:
Progress in biophysics and molecular biology More from this journal
Publication date:
2015-12-14
Acceptance date:
2015-12-02
DOI:
EISSN:
1873-1732
ISSN:
0079-6107
Language:
English
Keywords:
Pubs id:
pubs:587121
UUID:
uuid:aeab84ac-001d-440e-a91a-2c253cbcb232
Local pid:
pubs:587121
Source identifiers:
587121
Deposit date:
2016-02-22

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