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Anopheles gambiae laminin interacts with the P25 surface protein of Plasmodium berghei ookinetes.

Abstract:

Laminin is a major constituent of the basal lamina surrounding the midgut of the malaria vectors that has been implicated in the development of the Plasmodium oocyst. In this report we describe the cloning of the Anopheles gambiae gene encoding the laminin gamma 1 polypeptide and follow its expression during mosquito development. To further investigate the putative role of laminin in the transmission of the malaria parasite we studied the potential binding of the P25 surface protein of Plasmo...

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Authors


Vlachou, D More by this author
Sidén-Kiamos, I More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
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Journal:
Molecular and biochemical parasitology
Volume:
112
Issue:
2
Pages:
229-237
Publication date:
2001-02-05
DOI:
EISSN:
1872-9428
ISSN:
0166-6851
URN:
uuid:aeaa7c5a-f19a-4d86-8cb9-3f4836ddb0cf
Source identifiers:
260654
Local pid:
pubs:260654

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