Journal article icon

Journal article

‘Involve those who are managing these outbreaks’: stakeholders’ perspectives on the barriers and facilitators to the implementation of clinical management guidelines for high-consequence infectious diseases in Uganda—a thematic network analysis

Abstract:

Introduction 
Prior research highlighting the complexity of clinical management guidelines’ (CMGs) implementation during high consequence infectious disease (HCID) outbreaks has suggested that limited access to treatments and equipment and substantial issues regarding availability, inclusivity, quality and applicability hinders the implementation of CMGs in low- and middle-income countries (LMICs). This in-depth case study of Uganda—coincidentally occurring during the 2022 Sudan virus disease outbreak—aimed to explore contextual and supplementary factors which hinder or facilitate CMG development and implementation.

Methods 
Between August and December 2022, 43 interviews were conducted with medical personnel, consultant physicians, case managers and Uganda Ministry of Health officials. Interviews were analysed using a thematic network analysis approach to visualise thematic codes in qualitative data and highlight inherent relationships between codes.

Results 
Six thematic topics emerged as the main barriers to the implementation of CMGs during HCID outbreaks in Uganda: (1) deficient content and slow updates of CMGs; (2) scarce resources and healthcare disparities; (3) slow dissemination and limited access to guidelines; (4) improvisation of patient care (5) lack of training for healthcare workers (HCWs); and (6) limited pandemic preparedness and response infrastructure. Codes most strongly linked to facilitators and suggestions included: (1) HCW training in CMG implementation; (2) adequate resourcing; (3) involvement of personnel with prior HCID response experience in CMG development and (4) improvements in access to CMGs.

Conclusions 
By illustrating linkages to resource constraints, healthcare disparities, and limited surveillance and referral infrastructure, our study displays how insufficient training, patchy dissemination and slow updating exacerbate many of the underlying difficulties for CMG implementation in LMIC contexts. Findings offer valuable insights for LMICs to improve HCID outbreak responses and inform implementation of CMGs in future HCID outbreaks, where evidence is often initially limited. Recommendations to enhance CMG implementation are provided.

Publication status:
Published
Peer review status:
Peer reviewed

Actions

Access Document

Files:
Publisher copy:
10.1136/bmjph-2024-001165

Authors

More by this author
Role:
Author
ORCID:
0000-0001-9300-0066
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Pandemic Sciences Institute
Role:
Author
ORCID:
0000-0002-8270-6335
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Pandemic Sciences Institute
Role:
Author


More from this funder
Funder identifier:
https://ror.org/029chgv08
Grant:
215091/Z/18/Z


Publisher:
BMJ Publishing Group
Journal:
BMJ Public Health More from this journal
Volume:
3
Issue:
1
Article number:
e001165
Publication date:
2025-02-13
Acceptance date:
2024-12-30
DOI:
EISSN:
2753-4294
ISSN:
2753-4294


Language:
English
Pubs id:
2090305
Local pid:
pubs:2090305
Source identifiers:
2685000
Deposit date:
2025-02-14
ARK identifier:

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP