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Journal article

An in-depth analysis of original antigenic sin in dengue virus infection

Abstract:

The evolution of dengue viruses has resulted in four antigenically similar yet distinct serotypes. Infection with one serotype likely elicits lifelong immunity to that serotype, but generally not against the other three. Secondary or sequential infections are common, as multiple viral serotypes frequently cocirculate. Dengue infection, although frequently mild, can lead to dengue hemorrhagic fever (DHF) which can be life threatening. DHF is more common in seco...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1128/jvi.01826-10

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author


Publisher:
American Society for Microbiology
Journal:
Journal of Virology More from this journal
Volume:
85
Issue:
1
Pages:
410-421
Publication date:
2010-12-08
Acceptance date:
2010-10-14
DOI:
EISSN:
1098-5514
ISSN:
0022-538X


Keywords:
Pubs id:
pubs:206133
UUID:
uuid:aded06e0-8a55-413c-87c7-ece6f74cebe5
Local pid:
pubs:206133
Source identifiers:
206133
Deposit date:
2017-05-31
ARK identifier:

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