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External validation of a Cox prognostic model: principles and methods.

Abstract:

BACKGROUND: A prognostic model should not enter clinical practice unless it has been demonstrated that it performs a useful role. External validation denotes evaluation of model performance in a sample independent of that used to develop the model. Unlike for logistic regression models, external validation of Cox models is sparsely treated in the literature. Successful validation of a model means achieving satisfactory discrimination and calibration (prediction accuracy) in the validation sam...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1471-2288-13-33

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More from this funder
Name:
Cancer Research UK
Funding agency for:
Altman, D
Grant:
C5529
Publisher:
BioMed Central
Journal:
BMC medical research methodology More from this journal
Volume:
13
Issue:
1
Pages:
33
Publication date:
2013-01-01
DOI:
EISSN:
1471-2288
ISSN:
1471-2288
Language:
English
Keywords:
UUID:
uuid:add14c28-8561-45a9-9cc7-4b00258b0929
Local pid:
pubs:402022
Source identifiers:
402022
Deposit date:
2013-11-16

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