Journal article
Multicentre Collaborative Prospective Cohort Study Investigating the Impact of Enhanced Recovery After Surgery on Kidney Transplant Outcomes: The CRAFT Study
- Abstract:
- Perioperative complications are common in kidney transplantation. Enhanced recovery after surgery (ERAS) is a well-established multimodal perioperative care pathway designed to improve patient outcomes, however, its efficacy in renal transplant remains poorly described. Participating centres included adult renal transplant recipients and 30-day follow-up data. The primary outcome was LOS. Multivariable hierarchical models compared cohorts. 213 patients were included in the study period. 18/23 UK kidney transplant centres were represented. Analysis of the perioperative care delivery demonstrated similar patterns irrespective of reported protocols, with a tendency towards ERAS-type care. Between cohorts, the incidence of complications were similar; formal ERAS 14.3%, ERAS informal 17.0%, no ERAS 12.6%; p = 0.64. Median LOS was also similar; formal ERAS 6.0 days (5.0–11.5), informal ERAS 7.0 days (5.0–10.5) vs. no ERAS 6.0 days (5.0–10.5); p = 0.75. Readmissions were comparable; p = 0.721. Multivariable models confirmed these findings and demonstrated frailer patients had longer LOS and more readmissions. Currently, most UK renal transplant centres deliver a form of peri-operative ERAS care, indicating broad adoption of ERAS principles. Consequently, a formal ERAS protocol is not associated with decreased complications, LOS or readmissions. Efforts to improve outcomes should focus on prehabilitation of at-risk groups on the waiting list.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 4.7MB, Terms of use)
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- Publisher copy:
- 10.3389/ti.2025.15541
Authors
Contributors
+ Hackney, L
- Role:
- Contributor
+ McGrogan, D
- Role:
- Contributor
+ Tohill, C
- Role:
- Contributor
+ McBride, S
- Role:
- Contributor
+ Austin, I
- Role:
- Contributor
- Publisher:
- Frontiers Media
- Journal:
- Transplant International More from this journal
- Volume:
- 38
- Article number:
- 15541
- Publication date:
- 2026-01-14
- Acceptance date:
- 2025-12-12
- DOI:
- EISSN:
-
1432-2277
- ISSN:
-
0934-0874
- Language:
-
English
- Keywords:
- Pubs id:
-
2361422
- Local pid:
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pubs:2361422
- Source identifiers:
-
3661465
- Deposit date:
-
2026-01-14
- ARK identifier:
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- Copyright date:
- 2026
- Licence:
- CC Attribution (CC BY)
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