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Risk of recurrent subarachnoid haemorrhage, death, or dependence and standardised mortality ratios after clipping or coiling of an intracranial aneurysm in the International Subarachnoid Aneurysm Trial (ISAT): long-term follow-up.

Abstract:

BACKGROUND: Our aim was to assess the long-term risks of death, disability, and rebleeding in patients randomly assigned to clipping or endovascular coiling after rupture of an intracranial aneurysm in the follow-up of the International Subarachnoid Aneurysm Trial (ISAT). METHODS: 2143 patients with ruptured intracranial aneurysms were enrolled between 1994 and 2002 at 43 neurosurgical centres and randomly assigned to clipping or coiling. Clinical outcomes at 1 year have been previously repor...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher Version

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Publisher copy:
10.1016/s1474-4422(09)70080-8

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences, Neurovascular Research Unit
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences, Neurovascular Research Unit
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Centre for Statistics in Medicine
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences, Neurovascular Research Unit
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences, Neurovascular Research Unit
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Boston Scientific Corporation More from this funder
Publisher:
Elsevier B.V. Publisher's website
Journal:
The Lancet. Neurology Journal website
Volume:
8
Issue:
5
Pages:
427-433
Publication date:
2009-05-05
DOI:
EISSN:
1474-4465
ISSN:
1474-4422
URN:
uuid:ada1f973-21a6-47a8-b2cd-7486d8cc7dc5
Source identifiers:
294707
Local pid:
pubs:294707

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