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In vitro method to characterize diffusion of dye from polymeric particles: a model for drug release.

Abstract:

The release profile of a drug delivery system is a key factor in determining its efficacy. In the case of a polymeric particle based system, the release profile is a function of several parameters including particle diameter and porosity. The effects of these parameters are usually investigated experimentally using UV-spectroscopy. Predicting the drug release profile from particles as a result of the interaction of many parameters is desirable in order to facilitate the design of more efficie...

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Publisher copy:
10.1021/la900694k

Authors


Pancholi, K More by this author
Edirisinghe, M More by this author
Journal:
Langmuir : the ACS journal of surfaces and colloids
Volume:
25
Issue:
17
Pages:
10007-10013
Publication date:
2009-09-05
DOI:
EISSN:
1520-5827
ISSN:
0743-7463
URN:
uuid:ad79be27-2e34-4796-8153-1eebef4e6a86
Source identifiers:
327738
Local pid:
pubs:327738

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