In vitro method to characterize diffusion of dye from polymeric particles: a model for drug release.
The release profile of a drug delivery system is a key factor in determining its efficacy. In the case of a polymeric particle based system, the release profile is a function of several parameters including particle diameter and porosity. The effects of these parameters are usually investigated experimentally using UV-spectroscopy. Predicting the drug release profile from particles as a result of the interaction of many parameters is desirable in order to facilitate the design of more efficie...Expand abstract
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- Langmuir : the ACS journal of surfaces and colloids
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