Viscosupplementation for knee osteoarthritis: systematic review and meta-analysis

Journal article

Objective: To evaluate the effectiveness and safety of viscosupplementation for pain and function in patients with knee osteoarthritis. Design: Systematic review and meta-analysis of randomised trials. Data sources Searches were conducted of Medline, Embase, and the Cochrane Central Register of Controlled Trials (CENTRAL) databases from inception to 11 September 2021. Unpublished trials were identified from the grey literature and trial registries. Eligibility criteria for study sele...

Expand abstract

Authors: Pereira, TV; Jüni, P; Saadat, P; Xing, D; Yao, L

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: BMJ
• Journal: The BMJ
• Volume: 378
• Pages: e069722-e069722
• Publication date: 2022-07-06
• Acceptance date: 2022-05-23
• DOI: 10.1136/bmj-2022-069722
• ISSN: 1756-1833
• Language: English
• Keywords: Systematic review; Alternative medicine; Physical therapy; Internal medicine; Adverse effect; Relative risk; Meta-analysis; Intra articular; Medicine; Osteoarthritis; Placebo; Funnel plot; Clinical trial; Publication bias; Viscosupplementation; Confidence interval; Randomized controlled trial; MEDLINE