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Cumulative in-trial and post-trial effects of blood pressure and lipid lowering: systematic review and meta-analysis.

Abstract:

OBJECTIVE: Persistent long-term benefits after discontinuation of treatment have been suggested for blood pressure-lowering and lipid-lowering treatment. We conducted a systematic review to assess the long-term effects of blood pressure (BP) lowering (BPL) and lipid lowering on all-cause and cardiovascular mortality after discontinuation of randomized treatment.

METHODS: We systematically searched Medline, Embase, and the Cochrane Central Register of Controlled Trials. We inc...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1097/HJH.0000000000001233

Authors


Hirakawa, Y More by this author
Rodgers, A More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Obstetrics & Gynaecology
Chalmers, J More by this author
Publisher:
Lippincott, Williams & Wilkins Publisher's website
Journal:
Journal of Hypertension Journal website
Volume:
35
Issue:
5
Pages:
905–913
Publication date:
2017-01-05
Acceptance date:
2016-12-01
DOI:
EISSN:
1473-5598
ISSN:
0263-6352
Pubs id:
pubs:671091
URN:
uri:ad3f97c1-8746-4654-88d8-56cb9a1fe967
UUID:
uuid:ad3f97c1-8746-4654-88d8-56cb9a1fe967
Local pid:
pubs:671091

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